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Title: Positive inotropic effects of carbon monoxide-releasing molecules (CO-RMs) in the isolated perfused rat heart.
Authors: Musameh, MD
Fuller, BJ
Mann, BE
Green, CJ
Motterlini, R
First Published: Dec-2006
Citation: BR J PHARMACOL, 2006, 149 (8), pp. 1104-1112
Abstract: Carbon monoxide (CO) generated by the enzyme haeme oxygenase-1 (HO-1) during the breakdown of haeme is known to mediate a number of biological effects. Here, we investigated whether CO liberated from two water soluble carbon monoxide-releasing molecules (CO-RMs) exerts inotropic effects on the myocardium.
DOI Link: 10.1038/sj.bjp.0706939
ISSN: 0007-1188
Type: Journal Article
Appears in Collections:Published Articles, Dept. of Cardiovascular Sciences

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