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Title: Sequences flanking the repeat arrays of human minlsatellites: association with tandem and dispersed repeat elements
Authors: Armour John A. L.
Wong Zilla
Wilson Victoria
Royle Nicola J.
Jeffreys Alec J.
First Published: 11-Jul-1989
Publisher: Oxford University Press
Citation: Nucleic Acids Research, 1989, 17 (13), pp. 4925-4935
Abstract: We present DNA sequences flanking cloned hypervariable human minisatellites. In addition to providing confirmatory evidence that minisatellites cluster with other tandem repeats, these flanking sequences contain a high frequency of interspersed repetitive elements. These elements include a retroviral LTR-like sequence, from which one of the minisatellites appears to have expanded, and a recently described short interspersed repeat. We present our own findings concerning this element, in particular that those examples studied do not show significant evolutionary conservation, despite suggestions that the element may have a cis-acting function.
DOI Link: 10.1093/nar/17.13.4925
ISSN: 0305-1048
Type: Journal Article
Rights: Copyright © IRL Press, 1989
Appears in Collections:Published Articles, Dept. of Genetics

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