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Title: Post-genomic update on a classical candidate gene for coronary artery disease: ESR1.
Authors: Lucas, G
Lluís-Ganella, C
Subirana, I
Sentí, M
Willenborg, C
Musameh, MD
Schwartz, SM
O'Donnell, CJ
Melander, O
Salomaa, V
Elosua, R
CARDIoGRAM, Consortium
First Published: Dec-2011
Citation: CIRC CARDIOVASC GENET, 2011, 4 (6), pp. 647-654
Abstract: After age, sex is the most important risk factor for coronary artery disease (CAD). The mechanism through which women are protected from CAD is still largely unknown, but the observed sex difference suggests the involvement of the reproductive steroid hormone signaling system. Genetic association studies of the gene-encoding Estrogen Receptor α (ESR1) have shown conflicting results, although only a limited range of variation in the gene has been investigated.
DOI Link: 10.1161/CIRCGENETICS.111.960583
eISSN: 1942-3268
Type: Journal Article
Appears in Collections:Published Articles, Dept. of Cardiovascular Sciences

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