Please use this identifier to cite or link to this item:
Title: The new yeast is a mouse!
Authors: Borts, Rhona H.
First Published: May-2009
Publisher: Public Library of Science
Citation: PLoS Biology, 2009, 7 (5), e1000106
Abstract: In many organisms including yeast, mice, and humans, an essential feature of meiosis is genetic recombination. Recombination creates diversity by mixing the genetic information from each parent into new combinations. Recombination events can be either a reciprocal exchange of DNA called a crossover or a nonreciprocal exchange called a gene conversion or noncrossover (Figure 2). It is the crossovers that become part of a physical structure called chiasmata, which ensures that the homologous chromosomes go to opposite poles and thus partition properly. Because of this essential role, organisms have developed mechanisms (interference [1] and crossover homeostasis [2]) to distribute crossovers nonrandomly within and between chromosomes, such that each chromosome gets at least one crossover (the “obligate” chiasmata [3]). The molecular basis and the relationship between these mechanisms are poorly understood. [taken from introduction]
DOI Link: 10.1371/journal.pbio.1000106
ISSN: 1544-9173
eISSN: 1545-7885
Version: Publisher Version
Status: Peer-reviewed
Type: Journal Article
Rights: Copyright © 2009 Rhona Borts. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Appears in Collections:Published Articles, Dept. of Genetics

Files in This Item:
File Description SizeFormat 
pbio.1000106.pdfPublished (publisher PDF)1.52 MBUnknownView/Open

Items in LRA are protected by copyright, with all rights reserved, unless otherwise indicated.