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Title: Organelles maintain spindle position in plant meiosis
Authors: Brownfield, L.
Yi, J.
Jiang, H.
Minina, E. A.
Twell, David
Kohler, C.
First Published: 11-Mar-2015
Publisher: Nature Publishing Group
Citation: Nature Communications, 6:6492
Abstract: Accurate positioning of spindles is a critical aspect of cell division as it ensures that each daughter cell contains a single nucleus. In many flowering plants two meiotic chromosome separations occur without intervening cytokinesis, resulting in two spindles in one cell during the second division. Here we report a detailed examination of two mutants, jason (jas) and parallel spindle1 (ps1), in which disturbed spindle position during male meiosis II results in the incorporation of previously separated chromosome groups into a single cell. Our study reveals that an organelle band provides a physical barrier between the two spindles. The loss of a single protein, JAS, from this organelle band leads to its disruption and a random movement of the spindles. JAS is largely associated with vesicles in the organelle band, revealing a role for vesicles in plant meiosis and that cytoplasmic events maintain spindle position during chromosome division.
DOI Link: 10.1038/ncomms7492
eISSN: 2041-1723
Version: Post-print
Status: Peer-reviewed
Type: Journal Article
Rights: Archived with reference to SHERPA/RoMEO and publisher website. Version of record:
Description: Supplementary information is available at:
Appears in Collections:Published Articles, Dept. of Biology

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