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Title: Inter-Individual and Inter-Strain Variations in Zebrafish Locomotor Ontogeny
Authors: Lange, M.
Neuzeret, F.
Fabreges, B.
Froc, C.
Bedu, S.
Bally-Cuif, L.
Norton, William H. J.
First Published: 9-Aug-2013
Publisher: Public Library of Science
Citation: PLoS ONE, 2013, 8(8) : e70172
Abstract: Zebrafish exhibit remarkable alterations in behaviour and morphology as they develop from early larval stages to mature adults. In this study we compare the locomotion parameters of six common zebrafish strains from two different laboratories to determine the stability and repeatability of these behaviours. Our results demonstrate large variability in locomotion and fast swim events between strains and between laboratories across time. These data highlight the necessity for careful, strain-specific controls when analysing locomotor phenotypes and open up the possibility of standardising the quantification of zebrafish behaviour at multiple life stages.
DOI Link: 10.1371/journal.pone.0070172
ISSN: 1932-6203
Version: Publisher Version
Status: Peer-reviewed
Type: Journal Article
Rights: Copyright © 2013 Lange et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Appears in Collections:Published Articles, Dept. of Biology

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