Please use this identifier to cite or link to this item: http://hdl.handle.net/2381/32727
Title: Body Mass Index and Waist Circumference Cut-Points in Multi-Ethnic Populations from the UK and India: The ADDITION-Leicester, Jaipur Heart Watch and New Delhi Cross-Sectional Studies
Authors: Bodicoat, Danielle H.
Gray, Laura J.
Henson, Joseph
Webb, David
Guru, A.
Misra, A.
Gupta, R.
Vikram, N.
Sattar, N.
Davies, Melanie J.
Khunti, Kamlesh
First Published: 5-Mar-2014
Publisher: Public Library of Science
Citation: PLoS One, 2014, 9 (3), e90813
Abstract: AIMS: To derive cut-points for body mass index (BMI) and waist circumference (WC) for minority ethnic groups that are risk equivalent based on endogenous glucose levels to cut-points for white Europeans (BMI 30 kg/m[superscript: 2]; WC men 102 cm; WC women 88 cm). MATERIALS AND METHODS: Cross-sectional data from participants aged 40-75 years: 4,672 white and 1,348 migrant South Asian participants from ADDITION-Leicester (UK) and 985 indigenous South Asians from Jaipur Heart Watch/New Delhi studies (India). Cut-points were derived using fractional polynomial models with fasting and 2-hour glucose as outcomes, and ethnicity, objectively-measured BMI/WC, their interaction and age as covariates. RESULTS: Based on fasting glucose, obesity cut-points were 25 kg/m[superscript: 2] (95% Confidence Interval: 24, 26) for migrant South Asian, and 18 kg/m[superscript: 2] (16, 20) for indigenous South Asian populations. For men, WC cut-points were 90 cm (85, 95) for migrant South Asian, and 87 cm (82, 91) for indigenous South Asian populations. For women, WC cut-points were 77 cm (71, 82) for migrant South Asian, and 54 cm (20, 63) for indigenous South Asian populations. Cut-points based on 2-hour glucose were lower than these. CONCLUSIONS: These findings strengthen evidence that health interventions are required at a lower BMI and WC for South Asian individuals. Based on our data and the existing literature, we suggest an obesity threshold of 25 kg/m[superscript: 2] for South Asian individuals, and a very high WC threshold of 90 cm for South Asian men and 77 cm for South Asian women. Further work is required to determine whether lower cut-points are required for indigenous, than migrant, South Asians.
DOI Link: 10.1371/journal.pone.0090813
eISSN: 1932-6203
Links: http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0090813
http://hdl.handle.net/2381/32727
Version: Publisher Version
Status: Peer-reviewed
Type: Journal Article
Description: Copyright © 2014 Bodicoat et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Appears in Collections:Published Articles, Dept. of Health Sciences



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