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Title: Cardiometabolic risk factor response to a lifestyle intervention: a randomized trial
Authors: Harrington, Deirdre M.
Champagne, C. M.
Broyles, S. T.
Johnson, W. D.
Tudor-Locke, C.
Katzmarzyk, P. T.
First Published: 8-Jan-2015
Publisher: Mary Ann Liebert
Citation: Metabolic Syndrome and Related Disorders, 2015, 13 (3), pp. 125-131
Abstract: BACKGROUND: Strategies to increase adherence to national dietary and physical activity (PA) guidelines to improve the health in regions such as the Lower Mississippi Delta (LMD) of the United States are needed. Here we explore the cardiometabolic responses to an education and behavior change intervention among overweight and obese adults that adapted the 2010 Dietary Guidelines (DG), with and without a PA component. METHODS: White and African American overweight and obese adults were randomized to a DG group (n=61) or a DG+PA group (n=60). Both groups received a 12-week dietary education and behavior change intervention, and the DG+PA group also received a PA education and behavior change intervention with a pedometer. Changes in individual risk factors (blood pressure, fasting glucose, triglycerides, high-density lipoprotein cholesterol, and low-density lipoprotein cholesterol) and a continuous cardiometabolic risk score were determined. General linear models compared mean changes between groups, adjusting for covariates. RESULTS: No main effect of intervention group was found in completers (n=99) and those who engaged with ≥80% of the intervention (n=83) for individual risk factors or the continuous risk score. Pooling both groups, those with higher baseline risk factor values realized greater improvements in individual risk factors. CONCLUSIONS: Adapting DG did not produce any cardiometabolic benefits, even with a PA component. Although the sample was ostensibly healthy, they were all overweight to mildly obese (body mass index of 25-34.9 kg/m[superscript: 2]) and participants with higher baseline risk factor values showed more improvements. Adherence to longer-term behavior change may elicit changes in risk profile, so this should be explored.
DOI Link: 10.1089/met.2014.0112
ISSN: 1540-4196
eISSN: 1557-8518
Version: Post-print
Status: Peer-reviewed
Type: Journal Article
Rights: Copyright © 2015, Mary Ann Liebert. Final publication is available from Mary Ann Liebert, Inc., publishers
Appears in Collections:Published Articles, College of Medicine, Biological Sciences and Psychology

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