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|Title:||Excavating past population structures by surname-based sampling: the genetic legacy of the Vikings in northwest England|
|Authors:||Bowden, Georgina R.|
Balaresque, Patricia L.
King, Turi E.
Lee, Andrew C.
Roberts, Stephen J.
Jones, Abigail L.
Thomas, Mark G.
Harding, Stephen E.
Jobling, Mark A.
|Publisher:||Oxford University Press|
|Citation:||Molecular Biology and Evolution, 2008; 25(2): 301–309.|
|Abstract:||The genetic structures of past human populations are obscured by recent migrations and expansions, and can been observed only indirectly by inference from modern samples. However, the unique link between a heritable cultural marker, the patrilineal surname, and a genetic marker, the Y chromosome, provides a means to target sets of modern individuals that might resemble populations at the time of surname establishment. As a test case, we studied samples from the Wirral peninsula and West Lancashire, in northwest England. Place names and archaeology show clear evidence of a past Viking presence, but heavy immigration and population growth since the Industrial Revolution are likely to have weakened the genetic signal of a thousand-year-old Scandinavian contribution. Samples ascertained on the basis of two generations of residence were compared with independent samples based on known ancestry in the region, plus the possession of a surname known from historical records to have been present there in medieval times. The Y-chromosomal haplotypes of these two sets of samples are significantly different, and in admixture analyses the surname-ascertained samples show markedly greater Scandinavian ancestry proportions, supporting the idea that northwest England was once heavily populated by Scandinavian settlers. The method of historical surname-based ascertainment promises to allow investigation of the influence of migration and drift over the last few centuries in changing the population structure of Britain, and will have general utility in other regions where surnames are patrilineal and suitable historical records survive.|
|Rights:||This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License. (http://creativecommons.org/licenses/by-nc/2.0/uk/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.|
|Appears in Collections:||Published Articles, Dept. of Genetics|
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