Please use this identifier to cite or link to this item: http://hdl.handle.net/2381/32994
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dc.contributor.authorCarter, Patrice-
dc.contributor.authorGray, Laura J.-
dc.contributor.authorMorris, Danielle H.-
dc.contributor.authorDavies, Melanie J.-
dc.contributor.authorKhunti, Kamlesh-
dc.date.accessioned2015-09-01T13:34:45Z-
dc.date.available2015-09-01T13:34:45Z-
dc.date.issued2013-07-24-
dc.identifier.citationJournal of Nutritional Science, 2013, 2, pp. e21(5)en
dc.identifier.issn2048-6790-
dc.identifier.urihttp://journals.cambridge.org/action/displayAbstract?fromPage=online&aid=8952281&fileId=S2048679013000153en
dc.identifier.urihttp://hdl.handle.net/2381/32994-
dc.description.abstractIndividuals of South Asian origin are at high risk of developing type 2 diabetes; the relationship between this risk and diet remains to be investigated fully. Furthermore, fruit and vegetable intake remains low throughout the world and previous data suggest that intake is associated with risk of diabetes. The aim of this research study was to compare plasma vitamin C concentrations, measured as a biomarker for fruit and vegetable intake, in South Asian and white European individuals. Participants recruited as part of the Let's Prevent Diabetes Study provided samples for the quantification of plasma vitamin C. We compared vitamin C levels by ethnicity using multiple regression, both unadjusted and adjusted for confounders, including glycaemic status. Mean plasma vitamin C was significantly lower in the South Asian participants compared with white European participants (34.5 (sd 19·8) v. 39·9 (sd 22·1) µmol/l, respectively; P ≤ 0·0001). Significantly fewer South Asian individuals consumed five portions of fruit and vegetables per d, as determined by a plasma vitamin C concentration of ≥ 50 µmol/l (23·2 % (n 58) v. 31·4 % (n 558); P = 0·01). Vitamin C reflects habitual fruit and vegetable consumption; thus results suggest that South Asians have lower fruit and vegetable intake. However, it cannot be excluded that vitamin C is utilised differently. Dietary advice specifically targeting the South Asian population should be developed.en
dc.description.sponsorshipThe present study presents independent research commissioned by the National Institute for Health Research (NIHR) under its Programme Grants for Applied Research scheme (no. RP-PG-0606-1272) The project was supported by the NIHR Collaboration for Leadership in Applied Health Research and Care – Leicestershire, Northamptonshire and Rutland and The NIHR Leicester–Loughborough Diet, Lifestyle and Physical Activity Biomedical Research Unit which is a partnership between University Hospitals of Leicester NHS Trust, Loughborough University and the University of Leicester.en
dc.language.isoenen
dc.publisherNutrition Society: Journal of Nutritional Science, Cambridge University Press (CUP)en
dc.relation.urihttp://www.ncbi.nlm.nih.gov/pubmed/25191570-
dc.rightsCopyright © The Author(s) 2013 The online version of this article is published within an Open Access environment subject to the conditions of the Creative Commons Attribution-NonCommercial-ShareAlike licence <http://creativecommons.org/licenses/by-nc-sa/2.5/>. The written permission of Cambridge University Press must be obtained for commercial re-use.en
dc.subjectFruiten
dc.subjectNIHR, National Institute for Health Researchen
dc.subjectSouth Asiansen
dc.subjectT2DM, type 2 diabetes mellitusen
dc.subjectType 2 diabetesen
dc.subjectVegetablesen
dc.subjectVitamin Cen
dc.titleSouth Asian individuals at high risk of type 2 diabetes have lower plasma vitamin C levels than white Europeans.en
dc.typeJournal Articleen
dc.identifier.doi10.1017/jns.2013.15-
dc.identifier.eissn2048-6790-
dc.identifier.pii00015-
dc.description.statusPeer-revieweden
dc.description.versionPublisher Versionen
dc.type.subtypeJournal Article-
pubs.organisational-group/Organisationen
pubs.organisational-group/Organisation/COLLEGE OF MEDICINE, BIOLOGICAL SCIENCES AND PSYCHOLOGYen
pubs.organisational-group/Organisation/COLLEGE OF MEDICINE, BIOLOGICAL SCIENCES AND PSYCHOLOGY/School of Medicineen
pubs.organisational-group/Organisation/COLLEGE OF MEDICINE, BIOLOGICAL SCIENCES AND PSYCHOLOGY/School of Medicine/Department of Cardiovascular Sciencesen
pubs.organisational-group/Organisation/COLLEGE OF MEDICINE, BIOLOGICAL SCIENCES AND PSYCHOLOGY/School of Medicine/Department of Health Sciencesen
pubs.organisational-group/Organisation/COLLEGE OF MEDICINE, BIOLOGICAL SCIENCES AND PSYCHOLOGY/Themesen
pubs.organisational-group/Organisation/COLLEGE OF MEDICINE, BIOLOGICAL SCIENCES AND PSYCHOLOGY/Themes/Cardiovascularen
pubs.organisational-group/Organisation/COLLEGE OF MEDICINE, BIOLOGICAL SCIENCES AND PSYCHOLOGY/Themes/Populationen
dc.dateaccepted2013-04-25-
Appears in Collections:Published Articles, Dept. of Cardiovascular Sciences

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