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Title: Can community midwives prevent antenatal depression? An external pilot study to test the feasibility of a cluster randomized controlled universal prevention trial
Authors: Brugha, Traolach S.
Smith, Jane
Austin, Julia
Bankart, John
Patterson, Molly
Lovett, Caroline
Morgan, Zoe
Morrell, C. Jane
Slade, Pauline
First Published: 20-Oct-2015
Publisher: Cambridge University Press (CUP)
Citation: Psychological Medicine, 2016, 46 (2), pp. 345-356
Abstract: Background Repeated epidemiological surveys show no decline in depression although uptake of treatments has grown. Universal depression prevention interventions are effective in schools but untested rigorously in adulthood. Selective prevention programmes have poor uptake. Universal interventions may be more acceptable during routine healthcare contacts for example antenatally. One study within routine postnatal healthcare suggested risk of postnatal depression could be reduced in non-depressed women from 11% to 8% by giving health visitors psychological intervention training. Feasibility and effectiveness in other settings, most notably antenatally, is unknown. Method We conducted an external pilot study using a cluster trial design consisting of recruitment and enhanced psychological training of randomly selected clusters of community midwives (CMWs), recruitment of pregnant women of all levels of risk of depression, collection of baseline and outcome data prior to childbirth, allowing time for women ‘at increased risk’ to complete CMW-provided psychological support sessions. Results Seventy-nine percent of eligible women approached agreed to take part. Two hundred and ninety-eight women in eight clusters participated and 186 termed ‘at low risk’ for depression, based on an Edinburgh Perinatal Depression Scale (EPDS) score of <12 at 12 weeks gestation, provided baseline and outcome data at 34 weeks gestation. All trial protocol procedures were shown to be feasible. Antenatal effect sizes in women ‘at low risk’ were similar to those previously demonstrated postnatally. Qualitative work confirmed the acceptability of the approach to CMWs and intervention group women. Conclusion A fully powered trial testing universal prevention of depression in pregnancy is feasible, acceptable and worth undertaking.
DOI Link: 10.1017/S003329171500183X
ISSN: 0033-2917
eISSN: 1469-8978
Version: Published version (Publisher PDF)
Status: Peer-reviewed
Type: Journal Article
Rights: Copyright © Cambridge University Press 2015 This is an Open Access article, distributed under the terms of the Creative Commons Attribution licence (, which permits unrestricted re-use, distribution, and reproduction in any medium, provided the original work is properly cited.
Appears in Collections:Published Articles, Dept. of Health Sciences

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