Please use this identifier to cite or link to this item:
Title: Use of implicit and explicit bayesian methods in health technology assessment
Authors: Cooper, Nicola J.
Spiegelhalter, D.
Bujkiewicz, Sylwia
Dequen, Pascale
Sutton, Alex J.
First Published: 17-Jul-2013
Publisher: Cambridge University Press (CUP): HSS Journals
Citation: International Journal of Technology Assessment in Health Care, 2013, 29 (3), pp. 336-342
Abstract: OBJECTIVES: The aim of this study was to examine the use of implicit and explicit Bayesian methods in health technology assessments and to identify whether this has changed over time. METHODS: A review of all health technology assessment (HTA) reports of secondary research published by the UK National Institute of Health Research (NIHR) between 1997 and 2011. Data were extracted on the use and implementation of Bayesian methods, whether defined as such by the original authors (i.e., explicit) or not (i.e., implicit). RESULTS: A total of 155 of 375 (41 percent) NIHR HTA reports, identified as relevant to this review, contained a Bayesian analysis. Of these, 128 (83 percent) contained an implicit Bayesian analysis, 3 (2 percent) an explicit Bayesian analysis and 24 (15 percent) both implicit and explicit Bayesian analyses. Of the twenty-seven reports that explicitly used Bayes theorem, only six included prior information in the form of (informative) prior distributions. Over time, the percentage of HTA reports that used Bayesian (implicit and/or explicit) methods increased from 0 percent in 1997 to nearly 80 percent in 2011. CONCLUSIONS: This review has shown that there has been an increase in the use of Bayesian methods in HTA, which is likely to be a result of the increase in freely available resources to implement the approach. Areas where Bayesian methods have the potential to advance healthcare evaluations in the future are considered in the discussion.
DOI Link: 10.1017/S0266462313000354
eISSN: 1471-6348
Version: Post-print
Status: Peer-reviewed
Type: Journal Article
Rights: Copyright © Cambridge University Press 2013. Deposited with reference to the publisher’s open access archiving policy, available at
Appears in Collections:Published Articles, Dept. of Health Sciences

Files in This Item:
File Description SizeFormat 
Bayesian methods in health technology assessment IJHTA 30 8 12 manuscript revised.docPost-review (final submitted)227.5 kBMicrosoft WordView/Open
Bayesian methods in health technology assessment IJHTA 30 8 12 manuscript revised.pdfPost-review (final submitted)287.48 kBAdobe PDFView/Open

Items in LRA are protected by copyright, with all rights reserved, unless otherwise indicated.