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Title: Innate Lymphoid Cells
Authors: Cousins, David J.
Weston, Cathryn
First Published: 2015
Publisher: Wiley
Citation: eLS, 2015, (In press)
Abstract: Innate lymphoid cells (ILCs) are white blood cells derived from a common progenitor in the bone marrow . They respond rapidly to a limited array of antigens at the site of infection to provide immediate protection . The first identified ILCs were natural killer cells. H owever, several non - cytotoxic members of the family have since been reported. All ILCs lack the rearranged antigen - receptors characteristic of T - and B - cells but can be similarly divided into three main groups based on cell surface markers and cytokine expression profiles. Like their adaptive immune response counterparts they play specific roles in p roviding host defence against different pathogens. In addition, there is growing evidence that ILCs can contribute to multiple inflammatory and auto immune diseases.
DOI Link: 10.1002/047001590X
Embargo on file until: 1-Jan-10000
Version: Post-print
Status: Peer-reviewed
Type: Journal Article
Rights: Copyright © 1999-2014 by John Wiley and Sons, Inc. All Rights Reserved.
Appears in Collections:Published Articles, Dept. of Infection, Immunity and Inflammation

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