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Title: Phacoemulsification Surgery in Eyes with Neovascular Age-Related Macular Degeneration
Authors: Grixti, A.
Papavasileiou, E.
Cortis, Dominic
Kumar, B. V.
Prasad, S.
First Published: 22-Jan-2014
Publisher: Hindawi Publishing Corporation
Citation: ISRN Ophthalmology Volume 2014 (2014), Article ID 417603, 6 pages
Abstract: Purpose. To evaluate the visual outcomes and effect of phacoemulsification surgery on the progression of neovascular agerelated macular degeneration (AMD). Methods. Retrospective, noncomparative, and interventional case series. Thirty eyes from 29 subjects with neovascular AMD treated with intravitreal antivascular endothelial growth factor (VEGF) injections who underwent phacoemulsification and had a postsurgery follow-up of 6 months were included. LogMAR best corrected visual acuity (BCVA) was assessed preoperatively; 1 month, 3 months, and 6 months postoperatively; and finally at the last visit. The frequency of antiVEGF therapy, calculated as the number of intravitreal injections per month, and central macular thickness (CMT) before and after cataract surgery were determined. Results. Median (range) logMAR BCVA was 0.69 (0.16 to 1.32) preoperatively; 0.55 (−0.04 to 1.32) at 1 month, 0.52 (−0.1 to 1.32) at 3 months, and 0.50 (0.0 to 1.32) at 6 months postoperatively; and 0.6 (0.0 to 1.4) at final visit (𝑃 = 0.0011). There was no difference in the frequency of anti-VEGF injections between the immediate 6 months before and after phacoemulsification, which was equal to 0.1667 injections per month (𝑃 = 0.6377). Median CMT measured 203 𝜇m preoperatively, which temporarily increased to 238 𝜇m at 1 month after surgery (𝑃 = 0.0093) and then spontaneously returned to baseline, measuring 212.5 𝜇m at 3 months postoperatively (𝑃 = 0.3811). Conclusion. Phacoemulsification surgery significantly improved vision in patients with neovascular AMD, with no increased need for anti-VEGF injections to keep the macula dry postoperatively
DOI Link: 10.1155/2014/417603
ISSN: 2090-5688
eISSN: 2090-5696
Version: Publisher Version
Status: Peer-reviewed
Type: Journal Article
Rights: Copyright © 2014 Andre Grixti et al. This is an open access article distributed under the Creative Commons Attribution License CC BY 3.0, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Appears in Collections:Published Articles, Dept. of Mathematics

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