Please use this identifier to cite or link to this item: http://hdl.handle.net/2381/36383
Title: "Attacks" or "Whistling": Impact of Questionnaire Wording on Wheeze Prevalence Estimates.
Authors: Pescatore, A. M.
Spycher, B. D.
Beardsmore, Caroline Sarah
Kuehni, C. E.
First Published: 26-Jun-2015
Publisher: Public Library of Science
Citation: PLoS One, 2015, 10 (6), e0131618
Abstract: BACKGROUND: Estimates of prevalence of wheeze depend on questionnaires. However, wording of questions may vary between studies. We investigated effects of alternative wording on estimates of prevalence and severity of wheeze, and associations with risk factors. METHODS: White and South Asian children from a population-based cohort (UK) were randomly assigned to two groups and followed up at one, four and six years (1998, 2001, 2003). Parents were asked either if their child ever had "attacks of wheeze" (attack group, N=535), or "wheezing or whistling in the chest" (whistling group, N=2859). All other study aspects were identical, including questions about other respiratory symptoms. RESULTS: Prevalence of wheeze ever was lower in the attack group than in the whistling group for all surveys (32 vs. 40% in white children aged one year, p<0.001). Prevalence of other respiratory symptoms did not differ between groups. Wheeze tended to be more severe in the attack group. The strength of association with risk factors was comparable in the two groups. CONCLUSIONS: The wording of questions on wheeze can affect estimates of prevalence, but has less impact on measured associations with risk factors. Question wording is a potential source of between-study-heterogeneity in meta-analyses.
DOI Link: 10.1371/journal.pone.0131618
eISSN: 1932-6203
Links: http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0131618
http://hdl.handle.net/2381/36383
Version: Publisher Version
Status: Peer-reviewed
Type: Journal Article
Rights: Copyright © 2015 Pescatore et al. This is an open access article distributed under the terms of the Creative Commons Attribution License ( http://creativecommons.org/licenses/by/4.0/ ), which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited
Appears in Collections:Published Articles, Dept. of Infection, Immunity and Inflammation

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