Please use this identifier to cite or link to this item: http://hdl.handle.net/2381/36464
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dc.contributor.authorWilmot, E. G.-
dc.contributor.authorDavies, Melanie J.-
dc.contributor.authorEdwardson, Charlotte L.-
dc.contributor.authorGorely, T.-
dc.contributor.authorKhunti, Kamlesh-
dc.contributor.authorNimmo, M.-
dc.contributor.authorYates, Thomas-
dc.contributor.authorBiddle, S. J.-
dc.date.accessioned2016-02-01T09:31:06Z-
dc.date.available2016-02-01T09:31:06Z-
dc.date.issued2011-12-08-
dc.identifier.citationBMC Public Health, 2011, 11 : 908en
dc.identifier.urihttp://bmcpublichealth.biomedcentral.com/articles/10.1186/1471-2458-11-908en
dc.identifier.urihttp://hdl.handle.net/2381/36464-
dc.description.abstractBACKGROUND: The rising prevalence of Type 2 Diabetes Mellitus (T2DM) is a major public health problem. There is an urgent need for effective lifestyle interventions to prevent the development of T2DM. Sedentary behaviour (sitting time) has recently been identified as a risk factor for diabetes, often independent of the time spent in moderate-to-vigorous physical activity. Project STAND (Sedentary Time ANd Diabetes) is a study which aims to reduce sedentary behaviour in younger adults at high risk of T2DM. METHODS/DESIGN: A reduction in sedentary time is targeted using theory driven group structured education. The STAND programme is subject to piloting and process evaluation in line with the MRC framework for complex interventions. Participants are encouraged to self-monitor and self-regulate their behaviour. The intervention is being assessed in a randomised controlled trial with 12 month follow up. Inclusion criteria are a) aged 18-40 years with a BMI in the obese range; b) 18-40 years with a BMI in the overweight range plus an additional risk factor for T2DM. Participants are randomised to the intervention (n = 89) or control (n = 89) arm. The primary outcome is a reduction in sedentary behaviour at 12 months as measured by an accelerometer (count < 100/min). Secondary outcomes include physical activity, sitting/lying time using the ActivPAL posture monitor, fasting and 2 h oral glucose tolerance test, lipids, inflammatory biomarkers, body weight, waist circumference, blood pressure, illness perceptions, and efficacy beliefs for behaviour change. CONCLUSIONS: This is the first UK trial to address sedentary behaviour change in a population of younger adults at risk of T2DM. The results will provide a platform for the development of a range of future multidisciplinary interventions in this rapidly expanding high-risk population. TRIAL REGISTRATION: Current controlled trials ISRCTN08434554, MRC project 91409.en
dc.language.isoenen
dc.publisherBioMed Centralen
dc.relation.urihttp://www.ncbi.nlm.nih.gov/pubmed/22151909-
dc.rightsCopyright © Wilmot et al; licensee BioMed Central Ltd. 2011. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://​creativecommons.​org/​licenses/​by/​2.​0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.en
dc.subjectAdolescenten
dc.subjectAdulten
dc.subjectDiabetes Mellitus, Type 2en
dc.subjectGreat Britainen
dc.subjectHealth Promotionen
dc.subjectHumansen
dc.subjectInterviews as Topicen
dc.subjectResearch Designen
dc.subjectRisk Reduction Behavioren
dc.subjectSedentary Lifestyleen
dc.subjectYoung Adulten
dc.titleRationale and study design for a randomised controlled trial to reduce sedentary time in adults at risk of type 2 diabetes mellitus: project stand (Sedentary Time ANd diabetes)en
dc.typeJournal Articleen
dc.identifier.doi10.1186/1471-2458-11-908-
dc.identifier.eissn1471-2458-
dc.identifier.pii1471-2458-11-908-
dc.description.statusPeer-revieweden
dc.description.versionPublisher Versionen
dc.type.subtypeJournal Article;Randomized Controlled Trial;Research Support, Non-U.S. Gov't-
pubs.organisational-group/Organisationen
pubs.organisational-group/Organisation/COLLEGE OF MEDICINE, BIOLOGICAL SCIENCES AND PSYCHOLOGYen
pubs.organisational-group/Organisation/COLLEGE OF MEDICINE, BIOLOGICAL SCIENCES AND PSYCHOLOGY/School of Medicineen
pubs.organisational-group/Organisation/COLLEGE OF MEDICINE, BIOLOGICAL SCIENCES AND PSYCHOLOGY/School of Medicine/Department of Cardiovascular Sciencesen
pubs.organisational-group/Organisation/COLLEGE OF MEDICINE, BIOLOGICAL SCIENCES AND PSYCHOLOGY/School of Medicine/Department of Health Sciencesen
pubs.organisational-group/Organisation/COLLEGE OF MEDICINE, BIOLOGICAL SCIENCES AND PSYCHOLOGY/Themesen
pubs.organisational-group/Organisation/COLLEGE OF MEDICINE, BIOLOGICAL SCIENCES AND PSYCHOLOGY/Themes/Cardiovascularen
pubs.organisational-group/Organisation/COLLEGE OF MEDICINE, BIOLOGICAL SCIENCES AND PSYCHOLOGY/Themes/Populationen
dc.dateaccepted2011-12-08-
Appears in Collections:Published Articles, Dept. of Cardiovascular Sciences



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