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Title: High levels of neurological involvement but low mortality in miliary tuberculosis: a six-year case-series from the United Kingdom
Authors: Pareek, Manish
Venkatraman, Navin
King, Thomas
Bell, David
Woltmann, Gerrit
Wiselka, Martin
Abubakar, I.
First Published: 4-Feb-2016
Publisher: European Respiratory Society: ERJ
Citation: European Respiratory Journal, 2016 (Published before press)
Abstract: Tuberculosis (TB) remains one of the biggest global health challenges. Whilst the greatest burden of active disease is seen in Asia and Africa [1], TB remains a significant issue in the UK. Miliary TB is one of the severest manifestations of TB disease [2–4]. Up-to-date clinicopathological data on miliary TB from the developed world are lacking. We undertook a comprehensive 6-year review (2007–2012) of cases presenting to a single UK centre with an ethnically diverse population with high levels of population exchange with the Indian Subcontinent and Africa. Miliary TB was defined as the presence of miliary nodules on thoracic imaging in patients who presented with symptoms compatible with the diagnosis and either culture of Mycobacterium tuberculosis complex or culture-negative patients with clinical and/or histological features compatible with TB who were commenced on a course of antituberculous therapy (ATT).
DOI Link: 10.1183/13993003.01958-2015
ISSN: 0903-1936
eISSN: 1399-3003
Version: Post-print
Status: Peer-reviewed
Type: Journal Article
Rights: Copyright © ERS 2016. All rights reserved. This is an author-submitted, peer-reviewed version of a manuscript that has been accepted for publication in the European Respiratory Journal, prior to copy-editing, formatting and typesetting. This version of the manuscript may not be duplicated or reproduced without prior permission from the copyright owner, the European Respiratory Society. The publisher is not responsible or liable for any errors or omissions in this version of the manuscript or in any version derived from it by any other parties. The final, copy-edited, published article, which is the version of record, is available without a subscription 18 months after the date of issue publication.
Appears in Collections:Published Articles, Dept. of Infection, Immunity and Inflammation

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