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Title: Proliferative and Non-Proliferative Lesions of the Rat and Mouse Soft Tissue, Skeletal Muscle and Mesothelium
Authors: Greaves, Peter
Chouinard, L.
Ernst, H.
Mecklenburg, L.
Pruimboom-brees, I. M.
Rinke, M.
Rittinghausen, S.
Thibault, S.
von Erichsen, J.
Yoshida, T.
First Published: 23-Sep-2014
Publisher: Japanese Society of Toxicologic Pathology
Citation: Journal of Toxicologic Pathology Vol. 26 (2013) No. 3_Suppl 3 suppl p. 1S-26S
Abstract: The INHAND Project (International Harmonization of Nomenclature and Diagnostic Criteria for Lesions in Rats and Mice) is a joint initiative of the Societies of Toxicologic Pathology from Europe (ESTP), Great Britain (BSTP), Japan (JSTP), and North America (STP) to develop an internationally accepted nomenclature for proliferative and nonproliferative lesions in laboratory animals. The purpose of this publication is to provide a standardized nomenclature for classifying lesions observed in the soft tissues including skeletal muscle as well as the mesothelium of rats and mice. The standardized nomenclature of lesions presented in this document is also available electronically on the Internet ( Sources of material included histopathology databases from government, academia, and industrial laboratories throughout the world. Content includes spontaneous developmental and aging lesions as well as those induced by exposure to test materials. A widely accepted and utilized international harmonization of nomenclature for lesions in soft tissues, skeletal muscle and mesothelium in laboratory animals will decrease confusion among regulatory and scientific research organizations in different countries and provide a common language to increase and enrich international exchanges of information among toxicologists and pathologists.
DOI Link: 10.1293/tox.26.1S
ISSN: 0914-9198
eISSN: 1881-915X
Version: Publisher Version
Status: Peer-reviewed
Type: Journal Article
Rights: ©2013 The Japanese Society of Toxicologic Pathology This is an open-access article distributed under the terms of the Creative Commons Attribution Non-Commercial No Derivatives (by-nc-nd) License <>.
Appears in Collections:Published Articles, Dept. of Cancer Studies and Molecular Medicine

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