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First PublishedTitleAuthor(s)Type
8-Feb-2016Cooling-induced SUMOylation of EXOSC10 down-regulates ribosome biogenesis.Knight, John R. P.; Bastide, Amandine; Peretti, Diego; Roobol, A.; Roobol, J.; Mallucci, Giovanna R.; Smales, C. M.; Willis, Anne E.Journal Article
29-Jun-1998C-Nap1, a novel centrosomal coiled-coil protein and candidate substrate of the cell cycle-regulated protein kinase Nek2.Fry, A. M.; Mayor, T.; Meraldi, P.; Stierhof, Y. D.; Tanaka, K.; Nigg, E. A.Journal Article
15-Jun-1995Cell cycle regulation of the activity and subcellular localization of Plk1, a human protein kinase implicated in mitotic spindle function.Golsteyn, R. M.; Mundt, K. E.; Fry, A. M.; Nigg, E. A.Journal Article
6-Aug-20157-(Pyrazol-4-yl)-3H-imidazo[4,5-b]pyridine-based derivatives for kinase inhibition: Co-crystallisation studies with Aurora-A reveal distinct differences in the orientation of the pyrazole N1-substituent.Bavetsias, V.; Pérez-Fuertes, Y.; McIntyre, Patrick J.; Atrash, B.; Kosmopoulou, M.; O'Fee, L.; Burke, R.; Sun, C.; Faisal, A.; Bush, K.; Avery, S.; Henley, A.; Raynaud, F. I.; Linardopoulos, S.; Bayliss, Richard; Blagg, J.Journal Article
11-Jan-2016Molecular mechanisms that underpin EML4-ALK driven cancers and their response to targeted drugsBayliss, Richard; Choi, Jene; Fennell, Dean A.; Fry, Andrew M.; Richards, Mark W.Journal Article
2-Jun-2017Evidence for shear-mediated Ca(2+) entry through mechanosensitive cation channels in human platelets and a megakaryocytic cell line.Ilkan, Zeki; Wright, Joy R.; Goodall, Alison H.; Gibbins, Jonathan M.; Jones, Chris I.; Mahaut-Smith, Martyn P.Journal Article
29-Nov-2016Disentangling polydispersity in the PCNA−p15PAF complex, a disordered, transient and multivalent macromolecular assemblyCordeiro, T. N.; Chen, P.-C.; De Biasio, Alfredo; Sibille, N.; Blanco, F. J.; Hub, J. S.; Crehuet, R.; Bernadó, P.Journal Article
30-May-2017Progressive Motor Neuron Pathology and the Role of Astrocytes in a Human Stem Cell Model of VCP-Related ALS.Hall, C. E.; Yao, Z.; Choi, M.; Tyzack, G. E.; Serio, A.; Luisier, R.; Harley, J.; Preza, E.; Arber, C.; Crisp, S. J.; Watson, P. M. D.; Kullmann, D. M.; Abramov, A. Y.; Wray, S.; Burley, R.; Loh, Samantha H.Y.; Martins, L. Miguel; Stevens, M. M.; Luscombe, N .M.; Sibley, C. R.; Lakatos, A.; Ule, J.; Gandhi, S.; Patani, R.Journal Article
28-Jan-2017Targeting Class I Histone Deacetylases in a "Complex" Environment.Millard, Christopher J.; Watson, Peter J.; Fairall, Louise; Schwabe, John W. R.Journal Article
19-Dec-2016M1 muscarinic allosteric modulators slow prion neurodegeneration and restore memory loss.Bradley, Sophie J.; Bourgognon, Julie-Myrtille; Sanger, Helen E.; Verity, Nicholas; Mogg, Adrian J.; White, David J.; Butcher, Adrian J.; Moreno, Julie A.; Molloy, Colin; Macedo-Hatch, Timothy; Edwards, Jennifer M.; Wess, Jurgen; Pawlak, Robert; Read, David J.; Sexton, Patrick M.; Broad, Lisa M.; Steinert, Joern R.; Mallucci, Giovanna R.; Christopoulos, Arthur; Felder, Christian C.; Tobin, Andrew B.Journal Article