Published Articles, Dept. of Molecular and Cell Biology : [129] Collection home page

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Collection's Items (Sorted by Submit Date in Descending order): 1 to 20 of 129
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First PublishedTitleAuthor(s)Type
16-May-2018Bitopic Binding Mode of an M1 Muscarinic Acetylcholine Receptor Agonist Associated with Adverse Clinical Trial Outcomes.Bradley, SJ; Molloy, C; Bundgaard, C; Mogg, AJ; Thompson, KJ; Dwomoh, L; Sanger, HE; Crabtree, MD; Brooke, SM; Sexton, PM; Felder, CC; Christopoulos, A; Broad, LM; Tobin, AB; Langmead, CJJournal Article
5-Jul-2016A Novel Allosteric Activator of Free Fatty Acid 2 Receptor Displays Unique Gi-functional Bias.Bolognini, D; Moss, CE; Nilsson, K; Petersson, AU; Donnelly, I; Sergeev, E; König, GM; Kostenis, E; Kurowska-Stolarska, M; Miller, A; Dekker, N; Tobin, AB; Milligan, GJournal Article
9-Jan-2019Organization of ATP-gated P2X1 receptor intracellular termini in apo and desensitized states.Fryatt, AG; Dayl, S; Stavrou, A; Schmid, R; Evans, RJJournal Article
Jun-2018A Pharmacogenetic Approach to the Treatment of Patients With PPARG Mutations.Agostini, M; Schoenmakers, E; Beig, J; Fairall, L; Szatmari, I; Rajanayagam, O; Muskett, FW; Adams, C; Marais, AD; O'Rahilly, S; Semple, RK; Nagy, L; Majithia, AR; Schwabe, JWR; Blom, DJ; Murphy, R; Chatterjee, K; Savage, DBJournal Article
14-Aug-2018Mitotic phosphorylation regulates Hsp72 spindle localization by uncoupling ATP binding from substrate releaseMukherjee, Manjeet; Sabir, Sarah; O’Regan, Laura; Sampson, Josephina; Richards, Mark W.; Huguenin-Dezot, Nicolas; Ault, James R.; Chin, Jason W.; Zhuravleva, Anastasia; Fry, Andrew M.; Bayliss, RichardJournal Article
13-Sep-2018Aster proteins facilitate nonvesicular plasma membrane to ER cholesterol transport in mammalian cellsSandhu, Jaspreet; Li, Shiqian; Fairall, Louise; Pfisterer, Simon G.; Gurnett, Jennifer E.; Xiao, Xu; Weston, Thomas A.; Vashi, Dipti; Ferrari, Alessandra; Orozco, Jose L.; Hartman, Celine L.; Strugatsky, David; Lee, Stephen D.; He, Cuiwen; Hong, Cynthia; Jiang, Haibo; Bentolila, Laurent A; Gatta, Alberto T.; Levine, Tim P.; Ferng, Annie; Lee, Richard; Ford, David A.; Young, Stephen G.; Ikonen, Elina; Schwabe, John W. R.; Tontonoz, PeterJournal Article
15-Oct-2018Transcription factor dimerization activates the p300 acetyltransferaseOrtega, Esther; Rengachari, Srinivasan; Ibrahim, Ziad; Hoghoughi, Naghmeh; Gaucher, Jonathan; Holehouse, Alex S.; Khochbin, Saadi; Panne, DanielJournal Article
12-Mar-2019Cytosolic glucosylceramide regulates endolysosomal function in Niemann-Pick type C disease.Wheeler, S; Haberkant, P; Bhardwaj, M; Tongue, P; Ferraz, MJ; Halter, D; Sprong, H; Schmid, R; Aerts, JMFG; Sullo, N; Sillence, DJJournal Article
Jul-2018Assessment of the Molecular Mechanisms of Action of Novel 4-Phenylpyridine-2-One and 6-Phenylpyrimidin-4-One Allosteric Modulators at the M1 Muscarinic Acetylcholine Receptors.van der Westhuizen, Emma T.; Spathis, Arthur; Khajehali, Elham; Jörg, Manuela; Mistry, Shailesh N.; Capuano, Ben; Tobin, Andrew B.; Sexton, Patrick M.; Scammells, Peter J.; Valant, Celine; Christopoulos, ArthurJournal Article
3-Aug-2018Structural and functional analysis of Dickkopf 4 (Dkk4): New insights into Dkk evolution and regulation of Wnt signaling by Dkk and Kremen proteins.Patel, S; Barkell, AM; Gupta, D; Strong, SL; Bruton, S; Muskett, FW; Addis, PW; Renshaw, PS; Slocombe, PM; Doyle, C; Clargo, A; Taylor, RJ; Prosser, CE; Henry, AJ; Robinson, MK; Waters, LC; Holdsworth, G; Carr, MDJournal Article
15-Jun-2018Structural basis of pyrrole polymerization in human porphobilinogen deaminasePluta, P; Roversi, P; Bernardo-Seisdedos, G; Rojas, AL; Cooper, JB; Gu, S; Pickersgill, RW; Millet, OJournal Article
6-Sep-2012Real-time transcriptional profiling of cellular and viral gene expression during lytic cytomegalovirus infectionMarcinowski, Lisa; Lidschreiber, Michael; Windhager, Lukas; Rieder, Martina; Bosse, Jens B.; Rädle, Bernd; Bonfert, Thomas; Györy, Ildiko; de Graaf, Miranda; Prazeres da Costa, Olivia; Rosenstiel, Philip; Friedel, Caroline C.; Zimmer, Ralf; Ruzsics, Zsolt; Dölken, LarsJournal Article
30-Nov-2015GFI1 proteins orchestrate the emergence of haematopoietic stem cells through recruitment of LSD1Thambyrajah, R; Mazan, M; Patel, R; Moignard, V; Stefanska, M; Marinopoulou, E; Li, Y; Lancrin, C; Clapes, T; Möröy, T; Robin, C; Miller, C; Cowley, S; Göttgens, B; Kouskoff, V; Lacaud, GJournal Article
9-Nov-2018Active intermixing of indirect and direct neurons builds the striatal mosaicTinterri, A; Menardy, F; Diana, M; Lokmane, L; Keita, M; Coulpier, F; Lemoine, S; Mailhes, C; Mathieu, B; Merchan-Sala, P; Campbell, K; Gyory, I; Grosschedl, R; Popa, D; Garel, SJournal Article
1-Aug-2017Anharmonic motions versus dynamic disorder at the Mg ion from the charge densities in pyrope (Mg3Al2Si3O12) crystals at 30 K: six of one, half a dozen of the other.Destro, R.; Ruffo, R.; Roversi, P.; Soave, R.; Loconte, L.; Lo Presti, L.Journal Article
22-Nov-2017Structural basis of cholesterol binding by a novel clade of dendritic cell modulators from ticks.Roversi, Pietro; Johnson, Steven; Preston, Stephen G.; Nunn, Miles A.; Paesen, Guido C.; Austyn, Jonathan M.; Nuttall, Patricia A.; Lea, Susan M.Journal Article
2-May-2017Identification and characterization of a heterotrimeric archaeal DNA polymerase holoenzyme.Yan, Jiangyu; Beattie, Thomas R.; Rojas, Adriana L.; Schermerhorn, Kelly; Gristwood, Tamzin; Trinidad, Jonathan C.; Albers, Sonja V.; Roversi, Pietro; Gardner, Andrew F.; Abrescia, Nicola G. A.; Bell, Stephen D.Journal Article
6-Jul-2018Small molecule G protein-coupled receptor kinase inhibitors attenuate GRK2-mediated desensitization of vasoconstrictor-induced arterial contractions.Rainbow, Richard D.; Brennan, Sean; Jackson, Robert; Beech, Alison J.; Bengreed, Amal; Waldschmidt, Helen V.; Tesmer, John J. G.; Challiss, R. A. John; Willets, Jonathon M.Journal Article
11-Jul-2018Mapping the binding site of the P2X receptor antagonist PPADS reveals the importance of orthosteric site charge and the cysteine-rich head region.Huo, Hong; Fryatt, Alistair G.; Farmer, Louise K.; Schmid, Ralf; Evans, Richard J.Journal Article
27-Nov-2017Methyl group assignment using pseudocontact shifts with PARAssignLescanne, Mathilde; Skinner, Simon P.; Blok, Anneloes; Timmer, Monika; Cerofolini, Linda; Fragai, Marco; Luchinat, Claudio; Ubbink, MarcellusJournal Article
Collection's Items (Sorted by Submit Date in Descending order): 1 to 20 of 129
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