Please use this identifier to cite or link to this item:
Title: Patient's perceptions of chronic kidney disease and their association with psychosocial and clinical outcomes: a narrative review
Authors: Clarke, Amy L.
Yates, Thomas
Smith, Alice C.
Chilcot, Joseph
First Published: 10-May-2016
Publisher: Oxford University Press (OUP) for European Renal Association - European Dialysis and Transplant Association (ERA-EDTA)
Citation: Clinical Kidney Journal, 2016, 9 (3), pp. 494-502
Abstract: Patients with chronic kidney disease (CKD) form organized beliefs regarding their illness and treatment. These perceptions influence the coping strategies employed by an individual to manage his/her illness and may act as a predictor for his/her willingness to engage in self-management behaviours. While illness perceptions have been identified as predictors of non-adherence, depression and mortality in dialysis patients, there is a paucity of research in CKD patients not requiring renal replacement therapy. This narrative review synthesizes the existing literature regarding the role of illness perceptions and associated clinical and psychosocial outcomes in non-dialysis CKD patients. Studies were identified following database searches of AMED, BNI, CINAHL, EMBASE, Health Business Elite, HMIC, Medline, PsycINFO and Google Scholar in January 2016. Despite the small evidence base, existing studies indicate that negative illness perceptions are associated with disease progression and a number of psychosocial outcomes in non-dialysis CKD patients. Evidence from other clinical populations suggests that illness perceptions are modifiable through psychological intervention, which may be most effective if delivered early before beliefs have the chance to become more established. Therefore, targeting illness perceptions in the earlier stages of CKD may be optimal. Further studies are now required to ascertain the mechanisms through which illness perceptions predict psychosocial and clinical outcomes in CKD patients and to ultimately test the efficacy of illness perception-based interventions.
DOI Link: 10.1093/ckj/sfw014
ISSN: 2048-8505
eISSN: 2048-8513
Version: Publisher Version
Status: Peer-reviewed
Type: Journal Article
Rights: Copyright © the authors, 2016. This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-commercial License (, which permits unrestricted use, distribution, and reproduction in any medium non-commercially, provided the original author and source are credited.
Appears in Collections:Published Articles, Dept. of Infection, Immunity and Inflammation

Items in LRA are protected by copyright, with all rights reserved, unless otherwise indicated.