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Title: Post-mortem computed tomography coaxial cutting needle biopsy to facilitate the detection of bacterioplankton using PCR probes as a diagnostic indicator for drowning
Authors: Rutty, Guy N.
Johnson, Christopher
Amoroso, Jasmin
Robinson, Claire
Bradley, Carina J.
Morgan, Bruno
First Published: 5-Nov-2016
Publisher: Springer Verlag (Germany) for International Academy of Legal Medicine
Citation: International Journal of Legal Medicine, 2016
Abstract: We report for the first time the use of coaxial cutting needle biopsy, guided by post-mortem computed tomography (PMCT), to sample internal body tissues for bacterioplankton PCR analysis to investigate drowning. This technical report describes the biopsy technique, the comparison of the needle biopsy and the invasive autopsy sampling results, as well as the PMCT and autopsy findings. By using this new biopsy sampling approach for bacterioplankton PCR, we have developed on previous papers describing the minimally invasive PMCT approach for the diagnosis of drowning. When such a system is used, the operator must take all precautions to avoid contamination of the core biopsy samples due to the sensitivity of PCR-based analytic systems.
DOI Link: 10.1007/s00414-016-1473-6
ISSN: 0937-9827
eISSN: 1437-1596
Version: Publisher Version
Status: Peer-reviewed
Type: Journal Article
Rights: This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://, which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made
Appears in Collections:Published Articles, Dept. of Cancer Studies and Molecular Medicine

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