Please use this identifier to cite or link to this item: http://hdl.handle.net/2381/39510
Title: Assessment of Continuous Pain in Newborns admitted to NICUs in 18 European Countries
Authors: Anand, Kanwaljeet J. S.
Eriksson, Mats
Boyle, Elaine M.
Avila-Alvarez, Alejandro
Andersen, Randi Dovland
Sarafidis, Kosmas
Polkki, Tarja
Matos, Cristina
Lago, Paola
Papadouri, Thalia
Attard-Montalto, Simon
Ilmoja, Mari-Liis
Simons, Sinno
Tameliene, Rasa
van Overmeire, Bart
Berger, Angelika
Dobrzanska, Anna
Schroth, Michael
Bergqvist, Lena
Courtois, Emilie
Rousseau, Jessica
Carbajal, Ricardo
The EUROPAIN survey working group of the NeoOpioid Consortium
First Published: 3-Mar-2017
Publisher: Wiley, Foundation Acta Pædiatrica
Citation: Acta Paediatrica, 2017
Abstract: Aim Continuous pain occurs routinely, even after invasive procedures, or inflammation and surgery, but clinical practices associated with assessments of continuous pain remain unknown. Methods A prospective cohort study in 243 Neonatal Intensive Care Units (NICUs) from 18 European countries recorded frequency of pain assessments, use of mechanical ventilation, sedation, analgesia, or neuromuscular blockade for each neonate upto 28 days after NICU admission. Results Only 2113/6648 (31·8%) of neonates received assessments of continuous pain, occurring variably among tracheal ventilation (TrV, 46·0%), noninvasive ventilation (NiV, 35·0%), and no ventilation (NoV, 20·1%) groups (p<0·001). Daily assessments for continuous pain occurred in only 10·4% of all neonates (TrV: 14·0%, NiV: 10·7%, NoV: 7·6%; p<0·001). More frequent assessments of continuous pain occurred in NICUs with pain guidelines, nursing champions, and surgical admissions prompted (all p<0·01), and for newborns <32 weeks gestational age, those requiring ventilation, or opioids, sedatives-hypnotics, general anesthetics (O-SH-GA) (all p<0·001), or surgery (p=0·028). Use of O-SH-GA drugs increased the odds for pain assessment in the TrV (OR:1·60, p<0·001) and NiV groups (OR:1·40, p<0·001). Conclusion Assessments of continuous pain occurred in less than one-third of NICU admissions, and daily in only 10% of neonates. NICU clinical practices should consider including routine assessments of continuous pain in newborns.
DOI Link: 10.1111/apa.13810
ISSN: 0803-5253
eISSN: 1651-2227
Links: http://onlinelibrary.wiley.com/doi/10.1111/apa.13810/abstract
http://hdl.handle.net/2381/39510
Embargo on file until: 3-Mar-2018
Version: Post-print
Status: Peer-reviewed
Type: Journal Article
Rights: Copyright © 2017, Wiley. Deposited with reference to the publisher’s open access archiving policy.
Description: The file associated with this record is under embargo until 12 months after publication, in accordance with the publisher's self-archiving policy. The full text may be available through the publisher links provided above.
Appears in Collections:Published Articles, Dept. of Health Sciences

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