Please use this identifier to cite or link to this item: http://hdl.handle.net/2381/39796
Title: Human Group 2 innate lymphoid cells do not express the IL-5 receptor
Authors: Wright, Adam K. A.
Weston, Cathryn
Rana, Batika M. J.
Brightling, Christopher E.
Cousins, David J.
First Published: 10-May-2017
Publisher: Elsevier for American Academy of Allergy, Asthma and Immunology
Citation: Journal of Allergy and Clinical Immunology, 2017
Abstract: Group 2 innate lymphoid cells (ILC2s) are upstream regulators of IL-5-dependent eosinophil function in asthma. We’ve shown that ILC2s do not express the IL-5R and thus IL-5R- dependent therapeutic interventions (e.g. Benralizumab) are unlikely to be mediated directly on ILC2s.
DOI Link: 10.1016/j.jaci.2017.04.025
ISSN: 0091-6749
1097-6825
Links: http://www.sciencedirect.com/science/article/pii/S0091674917307492
http://hdl.handle.net/2381/39796
Version: Publisher Version
Status: Peer-reviewed
Type: Journal Article
Rights: Copyright © the authors, 2017. This is an open-access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Appears in Collections:Published Articles, Dept. of Infection, Immunity and Inflammation

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