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Title: Survival in South Asian and white European patients after acute myocardial infarction; a UK historical cohort study.
Authors: Gholap, Nitin N.
Khunti, Kamlesh
Davies, Melanie J.
Bodicoat, Danielle H .
Squire, Iain B.
First Published: 11-Feb-2015
Publisher: BMJ Publishing Group with British Cardiovascular Society
Citation: Heart, 2015, 101, pp. 630-630 (636)
Abstract: Objective To examine the association between ethnicity and survival following acute myocardial infarction (AMI) in White European (WE) and South Asian (SA) patients from a multiethnic UK population. Methods Retrospective, cohort study of 4111 (N=730, 17.8% of SA ethnicity) hospitalised patients, with AMI from a tertiary coronary care centre in the UK, admitted between October 2002 and September 2008. The primary end point was all-cause mortality. The association of ethnicity with survival post AMI was assessed using the Cox regression analysis. Results Compared with WE patients, SA patients were on average younger (62.0 years vs 67.3 years) and had higher prevalence of cardiovascular risk factors including diabetes (39.7% vs 16.1%). During follow-up (median 912, range 1–2556, days), crude mortality rate was 22.6% in SA patients and 26.0% in WE patients (p=0.061). SA ethnicity did not show univariate (HR 0.85 (0.72 to 1.01)) or multivariate (HR, 1.12 (0.94 to 1.34)) association with mortality. Findings were similar for mortality during 0–30 days (1.30 (0.99 to 1.70)), >30 days−1 year (0.97 (0.67 to 1.40)), >1 year–3 years (1.21 (0.83 to 1.76)), >3 years (0.82 (0.47 to 1.41)), and for long-term mortality in survivors from 30 days (1.02 (0.81 to 1.29)). Conclusions When adjusted for differing prevalence of cardiovascular risk factors in the two ethnic groups, survival following AMI was similar for SA and WE patients in the UK.
DOI Link: 10.1136/heartjnl-2014-305730
ISSN: 1355-6037
eISSN: 1468-201X
Version: Pre-print
Type: Journal Article
Rights: Copyright © 2015, BMJ Publishing Group with British Cardiovascular Society. Deposited with reference to the publisher’s open access archiving policy.
Description: Pre-print archived as submitting author does not have author accepted manuscript available.
Appears in Collections:Published Articles, Dept. of Cardiovascular Sciences

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