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Title: Cerebral Hemodynamic Effects of Cheyne–Stokes Respiration in a Patient with Stroke
Authors: Nogueira, R. C.
Panerai, R. B.
Teixeira, M. J.
Robinson, Thompson Gordon
Bor-Seng-Shu, E.
First Published: 15-Mar-2017
Publisher: Elsevier
Citation: Journal of Stroke and Cerebrovascular Diseases, 2017, 26 (5), pp. e80-e82
Abstract: INTRODUCTION: Cheyne-Stokes respiration (CSR) and central sleep apnea (CSA) are common in patients with heart failure and/or stroke. We aim to describe the cerebrovascular effects of CSR during the acute phase of stroke in a heart failure patient. CASE REPORT: A 74-year-old male with previous dilated cardiomyopathy had sudden onset of right hemiparesis and aphasia. A transcranial Doppler was performed with continuous measurement of blood pressure (BP) (Finometer) and end-tidal CO2 (nasal capnography). Offline analysis of hemodynamic data disclosed relatively large periodic oscillations of both cerebral blood flow velocity and BP related to the CSR breathing pattern. Derivate variables from the cerebrovascular resistance were calculated (critical closing pressure and resistance-area product), demonstrating that there may be a myogenic impairment of cerebral blood flow (CBF) control in the affected hemisphere of this subgroup of patient. CONCLUSION: There is an impairment of CBF regulation in the affected hemisphere of the patient with ischemic stroke and CSR, highlighting the role of cerebral hemodynamic monitoring in this scenario.
DOI Link: 10.1016/j.jstrokecerebrovasdis.2017.02.026
eISSN: 1532-8511
Version: Post-print
Status: Peer-reviewed
Type: Journal Article
Rights: Copyright © 2017 National Stroke Association. After an embargo period this version of the paper will be an open-access article distributed under the terms of the Creative Commons Attribution-Non Commercial-No Derivatives License (, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.
Description: The file associated with this record is under embargo until 12 months after publication, in accordance with the publisher's self-archiving policy. The full text may be available through the publisher links provided above.
Appears in Collections:Published Articles, Dept. of Cardiovascular Sciences

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