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|Title: ||Walking and Inflammatory Markers in Individuals Screened for Type 2 Diabetes.|
|Authors: ||Yates, Thomas|
Davies, Melanie J.
Brady, Emer Margaret
|Issue Date: ||3-Jul-2008|
|Citation: ||Preventive Medicine, 2008, 47 (4), pp. 417-421.|
|Abstract: ||Objective: To investigate the association of walking activity with inflammatory markers and fasting insulin in a bi-ethnic population screened for type 2 diabetes in Leicester, United Kingdom, between 2005 and 2006.
Method: Physical activity, adipocytokine, high-sensitivity C-reactive protein and fasting insulin measurements were available for 400 individuals screened for type 2 diabetes. Of the 400 participants, 56% were diagnosed with normal glucose control, 36% with prediabetes and 8% with diabetes.
Results: Multivariate statistical analysis showed that those who reported walking for at least 30 minutes on at least five days per week had lower levels of C-reactive protein, interleukin-6, and tumor necrosis factor-α compared to those who reported lower walking activity levels, after adjustment for other modes of moderate-to-vigorous physical activity, age, ethnicity, sex, social deprivation and smoking staus. Further adjustment for waist circumference attenuated the association of walking with tumor necrosis factor-α.
Conclusion: Walking activity, independent of other forms of physical activity, is associated with lower levels of circulating pro-inflammatory markers.|
|Description: ||This is the author’s final draft of the paper published as Preventive Medicine, 2008, 47 (4), pp. 417-421. The final published version is available at http://www.elsevier.com, Doi: 10.1016/j.ypmed.2008.06.015.|
|Appears in Collections:||Published Articles, Dept. of Health Sciences|
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