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Title: Detection of multiple fluorescent labels using superconducting tunnel junction detectors.
Authors: Fraser, G. W.
Heslop-Harrison, J. S. (Pat)
Schwarzacher, T.
Holland, A. D.
Verhoeve, P.
Peacock, A.
First Published: Sep-2003
Publisher: American Institute of Physics
Citation: Review of Scientific Instruments, 2003, 74 (9), pp. 4140-4144
Abstract: We show that cryogenically cooled, photon counting superconducting tunnel junctions ~STJs! can be used to simultaneously record the optical spectra from multiple biological fluorochromes. Measurements with a single-pixel tantalum STJ with a wavelength resolving power R5l/Dl of about 10 confirm the expected sensitivity advantage with respect to the photomultiplier-based detectors commonly used to record signals from microarrays and other fluorescent biological systems.
DOI Link: 10.1063/1.1599059
ISSN: 0034-6748
eISSN: 1089-7623
Type: Article
Description: This is the version as published by American Instiitute of physics. It is available online at
Appears in Collections:Published Articles, Dept. of Biology

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