Please use this identifier to cite or link to this item: http://hdl.handle.net/2381/43247
Title: Development of a computationally-designed polymeric adsorbent specific for mycotoxin patulin.
Authors: Piletska, EV
Pink, D
Karim, K
Piletsky, SA
First Published: 6-Nov-2017
Publisher: Royal Society of Chemistry
Citation: Analyst, 2017, 142 (24), pp. 4678-4683
Abstract: Patulin is a toxic compound which is found predominantly in apples affected by mould rot. Since apples and apple-containing products are a popular food for the elderly, children and babies, the monitoring of the toxin is crucial. This paper describes a development of a computationally-designed polymeric adsorbent for the solid-phase extraction of patulin, which provides an effective clean-up of the food samples and allows the detection and accurate quantification of patulin levels present in apple juice using conventional chromatography methods. The developed bespoke polymer demonstrates a quantitative binding towards the patulin present in undiluted apple juice. The polymer is inexpensive and easy to mass-produce. The contributing factors to the function of the adsorbent is a combination of acidic and basic functional monomers producing a zwitterionic complex in the solution that formed stronger binding complexes with the patulin molecule. The protocols described in this paper provide a blueprint for the development of polymeric adsorbents for other toxins or different food matrices.
DOI Link: 10.1039/c7an01294b
eISSN: 1364-5528
Links: https://pubs.rsc.org/en/Content/ArticleLanding/2017/AN/C7AN01294B#!divAbstract
http://hdl.handle.net/2381/43247
Version: Post-print
Status: Peer-reviewed
Type: Journal Article
Rights: Copyright © 2017, Royal Society of Chemistry. Deposited with reference to the publisher’s open access archiving policy. (http://www.rioxx.net/licenses/all-rights-reserved)
Appears in Collections:Published Articles, Dept. of Chemistry

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