Please use this identifier to cite or link to this item: http://hdl.handle.net/2381/43631
Title: Riding the wave of genomics to investigate aquatic coliphage diversity and activity.
Authors: Michniewski, S
Redgwell, T
Grigonyte, A
Rihtman, B
Aguilo-Ferretjans, M
Christie-Oleza, J
Jameson, E
Scanlan, DJ
Millard, AD
First Published: 18-Mar-2019
Publisher: Wiley for Society for Applied Microbiology (SfAM)
Citation: Environmental Microbiology, 2019
Abstract: Bacteriophages infecting Escherichia coli (coliphages) have been used as a proxy for faecal matter and water quality from a variety of environments. However, the diversity of coliphages that are present in seawater remains largely unknown, with previous studies largely focusing on morphological diversity. Here, we isolated and characterised coliphages from three coastal locations in the UK and Poland. Comparative genomics and phylogenetic analysis of phage isolates facilitated the identification of putative new species within the genera Rb69virus and T5virus and a putative new genus within the subfamily Tunavirinae. Furthermore, genomic and proteomic analysis combined with host range analysis allowed the identification of putative tail fibre that is likely responsible for the observed differences in host range of phages vB_Eco_mar003J3 and vB_Eco_mar004NP2.
DOI Link: 10.1111/1462-2920.14590
eISSN: 1462-2920
Links: https://onlinelibrary.wiley.com/doi/abs/10.1111/1462-2920.14590
http://hdl.handle.net/2381/43631
Embargo on file until: 18-Mar-2020
Version: Post-print
Status: Peer-reviewed
Type: Journal Article
Rights: Copyright © 2019, Wiley for Society for Applied Microbiology (SfAM). Deposited with reference to the publisher’s open access archiving policy. (http://www.rioxx.net/licenses/all-rights-reserved)
Description: The file associated with this record is under embargo until 12 months after publication, in accordance with the publisher's self-archiving policy. The full text may be available through the publisher links provided above.
Appears in Collections:Published Articles, Dept. of Infection, Immunity and Inflammation

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