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Title: A novel high sensitivity bacteriophage based assay identifies low level M.tuberculosis bacteraemia in immunocompetent patients with active and incipient TB
Authors: Verma, Raman
Swift, Benjamin M. C.
Wade, Handley-Hartill
Lee, Joanne K.
Woltmann, Gerrit
Rees, Catherine E. D.
Pranabashis, Haldar
First Published: 2019
Publisher: Oxford University Press (OUP), Infectious Diseases Society of America
Citation: Clinical Infectious Diseases, 2019, In Press
Abstract: Haematogenous dissemination of M. tuberculosis (Mtb) is critical to pathogenesis of progressive tuberculous infection in animal models. Using a novel phage-based blood assay, we report the first concordant evidence in well-characterised immunocompetent human cohorts, demonstrating associations of Mtb bacteraemia with progressive phenotypes of latent infection and active pulmonary TB respectively.
ISSN: 1058-4838
Links: TBA
Embargo on file until: 1-Jan-10000
Version: Post-print
Status: Peer-reviewed
Type: Journal Article
Rights: Copyright © 2019, Oxford University Press (OUP), Infectious Diseases Society of America. Deposited with reference to the publisher’s open access archiving policy. (
Description: The file associated with this record is under embargo until 12 months after publication, in accordance with the publisher's self-archiving policy. The full text may be available through the publisher links provided above.
Appears in Collections:Published Articles, Dept. of Infection, Immunity and Inflammation

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