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Title: Diversity of 26-locus Y-STR haplotypes in a Nepalese population sample: isolation and drift in the Himalayas.
Authors: Parkin, Emma J.
Kraayenbrink, Thirsa
Opgenort, Jean Robert M. L.
van Driem, George L.
Man Tuladhar, Nirmal
de Knijff, Peter
Jobling, Mark A.
First Published: Mar-2007
Publisher: Elsevier
Citation: Forensic Science International, 2007, 166(2-3), pp. 176-181.
Abstract: 26 Y-chromosomal short tandem repeat (STR) loci were amplified in a sample of 769 unrelated males from Nepal, using two multiplex polymerase chain reaction (PCR) assays. The 26 loci gave a discriminating power of 0.997, with 59% unique haplotypes, and the highest frequency haplotype occurring 12 times. We identified novel alleles at four loci, microvariants at a further two, and nine examples of amelogenin-Y deletions (1.2%). Comparison with a similarly sized Bhutanese sample typed with the same markers suggested histories of isolation and drift, with drift having a greater effect in Bhutan. Extended (11-locus) haplotypes for the Nepalese samples have been submitted to the Y-STR Haplotype Reference Database.
DOI Link: 10.1016/j.forsciint.2006.05.007
Type: Article
Rights: This is the author's draft of the article published in Forensic Science International
Appears in Collections:Published Articles, Dept. of Genetics

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