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|Title:||Diversity of 26-locus Y-STR haplotypes in a Nepalese population sample: isolation and drift in the Himalayas.|
|Authors:||Parkin, Emma J.|
Opgenort, Jean Robert M.L.
van Driem, George L.
Man Tuladhar, Nirmal
de Knijff, Peter
Jobling, Mark A.
|Citation:||Forensic Science International, 2007, 166(2-3), pp. 176-181.|
|Abstract:||26 Y-chromosomal short tandem repeat (STR) loci were amplified in a sample of 769 unrelated males from Nepal, using two multiplex polymerase chain reaction (PCR) assays. The 26 loci gave a discriminating power of 0.997, with 59% unique haplotypes, and the highest frequency haplotype occurring 12 times. We identified novel alleles at four loci, microvariants at a further two, and nine examples of amelogenin-Y deletions (1.2%). Comparison with a similarly sized Bhutanese sample typed with the same markers suggested histories of isolation and drift, with drift having a greater effect in Bhutan. Extended (11-locus) haplotypes for the Nepalese samples have been submitted to the Y-STR Haplotype Reference Database.|
|Description:||This is the author's draft of the article published in Forensic Science International www.elsevier.com/locate/forsciint|
|Appears in Collections:||Published Articles, Dept. of Genetics|
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