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Title: Microglia, Monocytes, and the Recurrence of Anxiety in Stress-Sensitized Mice.
Authors: Kronenberg, Golo
Uhlemann, Ria
Endres, Matthias
Gertz, Karen
First Published: 8-Mar-2019
Publisher: Elsevier for Society of Biological Psychiatry
Citation: Biological Psychiatry, 2019, 85 (12), pp. e67-e68
Abstract: To the Editor: We read with great interest the article by Weber et al. (1) in Biological Psychiatry describing the effects of microglia elimination and repopulation on stress sensitization induced by repeated social defeat (RSD). The article highlights brain-immune interactions and, in particular, the importance of stress-primed microglia for monocyte accumulation in the brain of RSD-sensitized mice following acute stress. The transcriptomic analysis of microglia 24 days after RSD could be very useful to other researchers, so the authors may wish to make this information accessible to the community by depositing it to an appropriate data repository.
DOI Link: 10.1016/j.biopsych.2018.11.027
eISSN: 1873-2402
Embargo on file until: 8-Mar-2020
Version: Post-print
Status: Peer-reviewed
Type: Journal Article
Rights: Copyright © Elsevier 2019. After an embargo period this version of the paper will be an open-access article distributed under the terms of the Creative Commons Attribution-Non Commercial-No Derivatives License (, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.
Description: The file associated with this record is under embargo until 12 months after publication, in accordance with the publisher's self-archiving policy. The full text may be available through the publisher links provided above.
Appears in Collections:Published Articles, Dept. of Cardiovascular Sciences

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