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Title: Dual role of complement in adipose tissue
Authors: Pattrick, Michael
Luckett, Jeni C.
Yue, Liang
Stover, Cordula M.
First Published: Feb-2009
Publisher: Elsevier
Citation: Molecular Immunology, 2009, 46 (5), pp. 755-760.
Abstract: Once thought of as purely the body’s chief energy store, adipose tissue and its constituent adipocytes have emerged as both a metabolic entity and an endocrine one. Complement is generally thought of as originating mainly from hepatic synthesis but also from synthesis by the macrophage phagocyte system. This review revisits early descriptions of adipocytic synthesis of complement components and highlights the need of a systematic analysis of the contribution of adipose tissue to systemic inflammation in order to appreciate the immunological activity of this tissue.
DOI Link: 10.1016/j.molimm.2008.09.013
ISSN: 0161-5890
Type: Article
Rights: This is the author's final draft of the paper published as Molecular Immunology, 2009, 46 (5), pp. 755-760. The final version is available from Doi: 10.1016/j.molimm.2008.09.013
Appears in Collections:Published Articles, Dept. of Infection, Immunity and Inflammation

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