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|Title: ||Comparative analysis of circadian clock genes in insects.|
|Authors: ||Sandrelli, F.|
Kyriacou, Charalambos P.
|Issue Date: ||Oct-2008|
|Publisher: ||Blackwell Publishing Ltd.|
|Citation: ||Insect Molecular Biology, 2008, 17 (5), 447-463.|
|Abstract: ||After a slow start, the comparative analysis of clock genes in insects has developed into a mature area of study in recent years. Brain transplant or surgical interventions in larger insects defined much of the early work in this area, before the cloning of clock genes became possible. We discuss the evolution of clock genes, their key sequence differences, and their likely modes of regulation in several different insect orders. We also present their expression patterns in the brain, focusing particularly on Diptera, Lepidoptera, and Orthoptera, the most common non-genetic model insects studied. We also highlight the adaptive involvement of clock molecules in other complex phenotypes which require biological timing, such as social behaviour, diapause and migration.|
|Description: ||This is the author's final draft of the paper published as Insect Molecular Biology, 2008, 17 (5), pp. 447-463. The definitive version is available at www.blackwell-synergy.com. Doi: 10.1111/j.1365-2583.2008.00832.x|
|Appears in Collections:||Published Articles, Dept. of Genetics|
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