Please use this identifier to cite or link to this item: http://hdl.handle.net/2381/491
Title: Comparison of MR pulse sequences in the detection of multiple sclerosis lesions
Authors: Yousry, T.A.
Filippi, Massimo
Becker, C.
Horsfield, Mark A.
Voltz, R.
First Published: 1997
Publisher: American Society of Neuroradiology.
Citation: American Journal of Neuroradiology, 1997, 18, pp.959-963.
Abstract: PURPOSE: To compare the sensitivity of conventional spin-echo, fast spin-echo, fast fluid-attenuated inversion recovery (FLAIR), and turbo gradient spin-echo MR sequences in the detection of multiple sclerosis lesions. METHODS: Conventional spin-echo, fast spin-echo, fast FLAIR, and turbo gradient spin-echo sequences were performed on a 1.0-T MR imager in seven patients with clinically definite multiple sclerosis. The images in each sequence were evaluated by two raters and consensus was reached by agreement. RESULTS: In comparing conventional spin-echo with fast spin-echo sequences, five lesions were seen only by conventional spin-echo and 63 were seen only by fast spin-echo; in comparing conventional spin-echo with fast FLAIR sequences, 18 lesions were seen only by conventional spin-echo and 109 only by fast FLAIR; in comparing conventional spin-echo with turbo gradient spin-echo sequences, 51 lesions were seen only by conventional spin-echo and seven only by turbo gradient spin-echo; in comparing fast spin-echo with fast FLAIR sequences, 45 lesions were seen only by fast spin-echo and 52 only by fast FLAIR. CONCLUSION: Fast spin-echo and fast FLAIR sequences improve the sensitivity of MR imaging in the detection of multiple sclerosis lesions with reduced acquisition time as compared with conventional spin-echo sequences. These sequences should therefore be considered for serial studies in patients with multiple sclerosis. The sensitivity of turbo gradient spin-echo was inferior to the other sequences, but its reduced acquisition time could make this technique the ideal choice for patients who cannot tolerate longer examination times.
Links: http://hdl.handle.net/2381/491
Type: Article
Description: This is the publshed version as it appears in American Journal Of Neuroradiology. It is available through their website at http://www.ajnr.org/cgi/reprint/18/5/959
Appears in Collections:Published Articles, Dept. of Cardiovascular Sciences

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