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Title: Directed DNA Metallization
Authors: Burley, G. A.
Gierlich, J.
Mofid, M. R.
Nir, H.
Tal, S.
Eichen, Y.
Carell, T.
First Published: 2006
Citation: Journal of the American Chemical Society, 2006, 128 (5), pp.1398-1399
Abstract: Genes of interest can be selectively metallized via the incorporation of modified triphosphates. These triphosphates bear functions that can be further derivatized with aldehyde groups via the use of click chemistry. Treatment of the aldehyde-labeled gene mixture with the Tollens reagent, followed by a development process, results in the selective metallization of the gene of interest in the presence of natural DNA strands.
DOI Link: 10.1021/ja055517v
ISSN: 0002-7863
Type: Article
Appears in Collections:Published Articles, Dept. of Chemistry

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