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First PublishedTitleAuthor(s)Type
22-Jan-2014Copy-number variation of the neuronal glucose transporter gene SLC2A3 and age of onset in Huntington's diseaseVittori, Angelica; Breda, Carlo; Repici, Mariaelena; Orth, Michael; Roos, Raymund A. C.; Outeiro, Tiago F.; Giorgini, Flaviano; Hollox, Edward J.; REGISTRY investigators of the European Huntington's Disease NetworkJournal Article
6-Feb-2015The transrepression arm of glucocorticoid receptor signaling is protective in mutant huntingtin-mediated neurodegenerationVaradarajan, S.; Breda, Carlo; Smalley, Joshua L.; Butterworth, Michael; Farrow, S. N.; Giorgini, Flaviano; Cohen, G. M.Journal Article
9-Oct-2014Rab11 modulates α-synuclein-mediated defects in synaptic transmission and behaviourBreda, Carlo; Nugent, Marie L.; Estranero, Jasper G.; Kyriacou, Charalambos P.; Outeiro, Tiago F.; Steinert, Joern R.; Giorgini, FlavianoJournal Article
6-Feb-2015The transrepression arm of glucocorticoid receptor signaling is protective in mutant huntingtin-mediated neurodegenerationVaradarajan, Shankar; Breda, Carlo; Smalley, Joshua L.; Butterworth, Michael; Farrow, Stuart N.; Giorgini, Flaviano; Cohen, Gerald M.Journal Article
10-May-2016Tryptophan-2,3-dioxygenase (TDO) inhibition ameliorates neurodegeneration by modulation of kynurenine pathway metabolitesBreda, Carlo; Sathyasaikumar, Korrapati V.; Sograte Idrissi, Shama; Notarangelo, Francesca M.; Estranero, Jasper G.; Moore, Gareth G. L.; Green, Edward W.; Kyriacou, Charalambos P.; Schwarcz, Robert; Giorgini, FlavianoJournal Article
2-Oct-2015Connectivity mapping uncovers small molecules that modulate neurodegeneration in Huntington's disease modelsSmalley, Joshua L.; Breda, Carlo; Mason, Robert P.; Kooner, Gurdeep; Luthi-Carter, Ruth; Gant, T. W.; Giorgini, FlavianoJournal Article
18-Nov-2016Glycation potentiates neurodegeneration in models of Huntington's diseaseVicente Miranda, H.; Gomes, M. A.; Branco-Santos, Joana; Breda, Carlo; Lázaro, D. F.; Lopes, L. V.; Herrera, F; Giorgini, Flaviano; Outeiro, T. F.Journal Article
28-Oct-2014α-Synuclein interacts with the switch region of Rab8a in a Ser129 phosphorylation-dependent manner.Yin, G.; Lopes da Fonseca, T.; Eisbach, S. E.; Anduaga, Ane Martín; Breda, Carlo; Orcellet, M. L.; Szegő, É. M.; Guerreiro, P.; Lázaro, D. F.; Braus, G. H.; Fernandez, C. O.; Griesinger, C.; Becker, S.; Goody, R. S.; Itzen, A.; Giorgini, Flaviano; Outeiro, T. F.; Zweckstetter, M.Journal Article
10-Apr-2017Glycation potentiates α-synuclein-associated neurodegeneration in synucleinopathiesMiranda, Hugo Vicente; Szego, E´ va M.; Oliveira, Luı´s M. A.; Breda, Carlo; Darendelioglu, Ekrem; de Oliveira, Rita M.; Ferreira, Diana G.; Gomes, Marcos A.; Rott, Ruth; Oliveira, Ma´rcia; Munar, Francesca; Enguita, Francisco J.; Simoes, Tania; Rodrigues, Eva F.; Heinrich, Michael; Martins, Ivo C.; Zamolo, Irina; Riess, Olaf; Cordeiro, Carlos; Ponces-Freire, Ana; Lashuel, Hilal A.; Santos, Nuno C.; Lopes, Luisa V.; Xiang, Wei; Jovin, Thomas M.; Penque, Deborah; Engelender, Simone; Zweckstetter, Markus; Klucken, Jochen; Giorgini, Flaviano; Quintas, Alexandre; Outeiro, Tiago F.Journal Article
9-Apr-2018Nitric oxide-mediated posttranslational modifications control neurotransmitter release by modulating complexin farnesylation and enhancing its clamping ability.Robinson, Susan W.; Bourgognon, Julie-Myrtille; Spiers, Jereme G.; Breda, Carlo; Campesan, Susanna; Butcher, Adrian; Mallucci, Giovanna R; Dinsdale, David; Morone, Nobuhiro; Mistry, Raj; Smith, Tim M.; Guerra-Martin, Maria; Challiss, R. A. John; Giorgini, Flaviano; Steinert, Joern R.Journal Article