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First PublishedTitleAuthor(s)Type
2009Exploiting yeast genetics to inform therapeutic strategies for Huntington's disease.Giorgini, Flaviano; Muchowski, PJJournal Article
28-Feb-2005Connecting the dots in Huntington's disease with protein interaction networksGiorgini, Flaviano; Muchowski, Paul J.Journal Article
Mar-2006Yeast as a drug discovery platform in Huntington's and Parkinson's diseases.Outeiro, TF; Giorgini, FlavianoJournal Article
Mar-2008Yeast as a model for studying human neurodegenerative disorders.Miller-Fleming, L; Giorgini, Flaviano; Outeiro, TFJournal Article
10-Jun-2011Kynurenine 3-monooxygenase inhibition in blood ameliorates neurodegeneration.Zwilling, D; Huang, SY; Sathyasaikumar, KV; Notarangelo, FM; Guidetti, P; Wu, HQ; Lee, J; Truong, J; Andrews-Zwilling, Y; Hsieh, EW; Louie, JY; Wu, T; Scearce-Levie, K; Patrick, C; Adame, A; Giorgini, Flaviano; Moussaoui, S; Laue, G; Rassoulpour, A; Flik, G; Huang, Y; Muchowski, JM; Masliah, E; Schwarcz, R; Muchowski, PJJournal Article
27-Nov-2012Parkinson's disease-associated mutations in DJ-1 modulate its dimerization in living cells.Repici, Mariaelena; Straatman, Kornelis R; Balduccio, Nadia; Enguita, Francisco J.; Outeiro, Tiago F.; Giorgini, FlavianoJournal Article
10-Apr-2013Structural basis of kynurenine 3-monooxygenase inhibitionAmaral, Marta; Levy, Colin; Heyes, Derren J.; Lafite, Pierre; Outeiro, Tiago F.; Giorgini, Flaviano; Leys, David; Scrutton, Nigel S.Journal Article
4-Aug-2014The small GTPase Rab11 co-localizes with α-synuclein in intracellular inclusions and modulates its aggregation, secretion and toxicityChutna, O.; Gonçalves, S.; Villar-Piqué, A.; Guerreiro, P.; Marijanovic, Z.; Mendes, T.; Ramalho, J.; Emmanouilidou, E.; Ventura, S.; Klucken, J.; Barral, D. C.; Giorgini, Flaviano; Vekrellis, K.; Outeiro, T. F.Journal Article
13-May-2014Yeast DJ-1 superfamily members are required for diauxic-shift reprogramming and cell survival in stationary phaseMiller-Fleming, L.; Antas, P.; Pais, T. F.; Smalley, J. L.; Giorgini, Flaviano; Outeiro, T. F.Journal Article
28-Oct-2014α-Synuclein interacts with the switch region of Rab8a in a Ser129 phosphorylation-dependent manner.Yin, G.; Lopes da Fonseca, T.; Eisbach, S. E.; Anduaga, Ane Martín; Breda, Carlo; Orcellet, M. L.; Szegő, É. M.; Guerreiro, P.; Lázaro, D. F.; Braus, G. H.; Fernandez, C. O.; Griesinger, C.; Becker, S.; Goody, R. S.; Itzen, A.; Giorgini, Flaviano; Outeiro, T. F.; Zweckstetter, M.Journal Article