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First PublishedTitleAuthor(s)Type
21-Feb-2012Exposure to anticancer drugs can result in transgenerational genomic instability in mice.Glen, CD; Dubrova, YEJournal Article
Aug-2010Environmental enrichment reduces neuronal intranuclear inclusion load but has no effect on messenger RNA expression in a mouse model of Huntington disease.Benn, CL; Luthi-Carter, R; Kuhn, A; Sadri-Vakili, G; Blankson, KL; Dalai, SC; Goldstein, DR; Spires, TL; Pritchard, J; Olson, JM; van Dellen A; Hannan, AJ; Cha, JHJournal Article
Aug-2011Altered chromatin architecture underlies progressive impairment of the heat shock response in mouse models of Huntington disease.Labbadia, J; Cunliffe, H; Weiss, A; Katsyuba, E; Sathasivam, K; Seredenina, T; Woodman, B; Moussaoui, S; Frentzel, S; Luthi-Carter, R; Paganetti, P; Bates, GPJournal Article
8-Jan-2010Human TUBB3 mutations perturb microtubule dynamics, kinesin interactions, and axon guidance.Tischfield, MA; Baris, HN; Wu, C; Rudolph, G; Van Maldergem L; He, W; Chan, WM; Andrews, C; Demer, JL; Robertson, RL; Mackey, DA; Ruddle, JB; Bird, TD; Gottlob, I; Pieh, C; Traboulsi, EI; Pomeroy, SL; Hunter, DG; Soul, JS; Newlin, A; Sabol, LJ; Doherty, EJ; de Uzcátegui CE; de Uzcátegui N; Collins, ML; Sener, EC; Wabbels, B; Hellebrand, H; Meitinger, T; de Berardinis T; Magli, A; Schiavi, C; Pastore-Trossello, M; Koc, F; Wong, AM; Levin, AV; Geraghty, MT; Descartes, M; Flaherty, M; Jamieson, RV; Møller, HU; Meuthen, I; Callen, DF; Kerwin, J; Lindsay, S; Meindl, A; Gupta, ML; Pellman, D; Engle, ECJournal Article
Feb-2012Pharmacological characterization of the bifunctional opioid ligand H-Dmt-Tic-Gly-NH-Bzl (UFP-505).Dietis, N; McDonald, J; Molinari, S; Calo, G; Guerrini, R; Rowbotham, DJ; Lambert, DGJournal Article
24-Mar-2011Benzimidazole inhibitors induce a DFG-out conformation of never in mitosis gene A-related kinase 2 (Nek2) without binding to the back pocket and reveal a nonlinear structure-activity relationship.Solanki, S; Innocenti, P; Mas-Droux, C; Boxall, K; Barillari, C; van Montfort RL; Aherne, GW; Bayliss, R; Hoelder, SJournal Article
Oct-2010Plasma metabolic profiling reveals age-dependency of systemic effects of green tea polyphenols in mice with and without prostate cancer.Teichert, F; Verschoyle, RD; Greaves, P; Jones, DJ; Wilson, ID; Farmer, PB; Steward, WP; Gescher, AJ; Keun, HCJournal Article
22-Jul-2010Imidazo[4,5-b]pyridine derivatives as inhibitors of Aurora kinases: lead optimization studies toward the identification of an orally bioavailable preclinical development candidate.Bavetsias, V; Large, JM; Sun, C; Bouloc, N; Kosmopoulou, M; Matteucci, M; Wilsher, NE; Martins, V; Reynisson, J; Atrash, B; Faisal, A; Urban, F; Valenti, M; de Haven Brandon A; Box, G; Raynaud, FI; Workman, P; Eccles, SA; Bayliss, R; Blagg, J; Linardopoulos, S; McDonald, EJournal Article
5-Aug-2010Biological, clinical and population relevance of 95 loci for blood lipids.Teslovich, TM; Musunuru, K; Smith, AV; Edmondson, AC; Stylianou, IM; Koseki, M; Pirruccello, JP; Ripatti, S; Chasman, DI; Willer, CJ; Johansen, CT; Fouchier, SW; Isaacs, A; Peloso, GM; Barbalic, M; Ricketts, SL; Bis, JC; Aulchenko, YS; Thorleifsson, G; Feitosa, MF; Chambers, J; Orho-Melander, M; Melander, O; Johnson, T; Li, X; Guo, X; Li, M; Shin Cho Y; Jin Go M; Jin Kim Y; Lee, JY; Park, T; Kim, K; Sim, X; Twee-Hee Ong R; Croteau-Chonka, DC; Lange, LA; Smith, JD; Song, K; Hua Zhao J; Yuan, X; Luan, J; Lamina, C; Ziegler, A; Zhang, W; Zee, RY; Wright, AF; Witteman, JC; Wilson, JF; Willemsen, G; Wichmann, HE; Whitfield, JB; Waterworth, DM; Wareham, NJ; Waeber, G; Vollenweider, P; Voight, BF; Vitart, V; Uitterlinden, AG; Uda, M; Tuomilehto, J; Thompson, JR; Tanaka, T; Surakka, I; Stringham, HM; Spector, TD; Soranzo, N; Smit, JH; Sinisalo, J; Silander, K; Sijbrands, EJ; Scuteri, A; Scott, J; Schlessinger, D; Sanna, S; Salomaa, V; Saharinen, J; Sabatti, C; Ruokonen, A; Rudan, I; Rose, LM; Roberts, R; Rieder, M; Psaty, BM; Pramstaller, PP; Pichler, I; Perola, M; Penninx, BW; Pedersen, NL; Pattaro, C; Parker, AN; Pare, G; Oostra, BA; O'Donnell, CJ; Nieminen, MS; Nickerson, DA; Montgomery, GW; Meitinger, T; McPherson, R; McCarthy, MI; McArdle, W; Masson, D; Martin, NG; Marroni, F; Mangino, M; Magnusson, PK; Lucas, G; Luben, R; Loos, RJ; Lokki, ML; Lettre, G; Langenberg, C; Launer, LJ; Lakatta, EG; Laaksonen, R; Kyvik, KO; Kronenberg, F; König, IR; Khaw, KT; Kaprio, J; Kaplan, LM; Johansson, A; Jarvelin, MR; Janssens, AC; Ingelsson, E; Igl, W; Kees Hovingh G; Hottenga, JJ; Hofman, A; Hicks, AA; Hengstenberg, C; Heid, IM; Hayward, C; Havulinna, AS; Hastie, ND; Harris, TB; Haritunians, T; Hall, AS; Gyllensten, U; Guiducci, C; Groop, LC; Gonzalez, E; Gieger, C; Freimer, NB; Ferrucci, L; Erdmann, J; Elliott, P; Ejebe, KG; Döring, A; Dominiczak, AF; Demissie, S; Deloukas, P; de Geus EJ; de Faire U; Crawford, G; Collins, FS; Chen, YD; Caulfield, MJ; Campbell, H; Burtt, NP; Bonnycastle, LL; Boomsma, DI; Boekholdt, SM; Bergman, RN; Barroso, I; Bandinelli, S; Ballantyne, CM; Assimes, TL; Quertermous, T; Altshuler, D; Seielstad, M; Wong, TY; Tai, ES; Feranil, AB; Kuzawa, CW; Adair, LS; Taylor, HA; Borecki, IB; Gabriel, SB; Wilson, JG; Holm, H; Thorsteinsdottir, U; Gudnason, V; Krauss, RM; Mohlke, KL; Ordovas, JM; Munroe, PB; Kooner, JS; Tall, AR; Hegele, RA; Kastelein, JJ; Schadt, EE; Rotter, JI; Boerwinkle, E; Strachan, DP; Mooser, V; Stefansson, K; Reilly, MP; Samani, NJ; Schunkert, H; Cupples, LA; Sandhu, MS; Ridker, PM; Rader, DJ; van Duijn CM; Peltonen, L; Abecasis, GR; Boehnke, M; Kathiresan, SJournal Article
Jul-2010Vascular endothelial growth factor enhances angiotensin II-induced aneurysm formation in apolipoprotein E-deficient mice.Choke, E; Cockerill, GW; Dawson, J; Howe, F; Wilson, WR; Loftus, IM; Thompson, MMJournal Article