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First PublishedTitleAuthor(s)Type
1-Apr-2005Soluble markers for the assessment of biological activity with PTK787/ZK 222584 (PTK/ZK), a vascular endothelial growth factor receptor (VEGFR) tyrosine kinase inhibitor in patients with advanced colorectal cancer from two phase I trialsDrevs, J; Zirrgiebel, U; Schmidt-Gersbach, CIM; Mross, K; Medinger, M; Lee, L; Pinheiro, J; Wood, J; Thomas, AL; Unger, C; Henry, A; Steward, WP; Laurent, D; Lebwohl, D; Dugan, M; Marme, DJournal Article
1-Feb-2000Angiogenesis and non-small cell lung cancerCox, G; Jones, JL; Walker, RA; Steward, WP; O'Byrne, KJJournal Article
1-Jan-2000The relationship between angiogenesis and the immune response in carcinogenesis and the progression of malignant diseaseO'Byrne, KJ; Dalgleish, AG; Browning, MJ; Steward, WP; Harris, ALJournal Article
1-Dec-2001Bcl-2 is an independent prognostic factor and adds to a biological model for predicting outcome in operable non-small cell lung cancerCox, G; Jones, JL; Andi, A; Abrams, KR; O'Byrne, KJJournal Article
1-Jun-2006Biomarkers for assessment of pharmacologic activity for a vascular endothelial growth factor (VEGF) receptor inhibitor, PTK787/ZK 222584 (PTK/ZK): translation of biological activity in a mouse melanoma metastasis model to phase I studies in patients with advanced colorectal cancer with liver metastasesLee, L; Sharma, S; Morgan, B; Allegrini, P; Schnell, C; Brueggen, J; Cozens, R; Horsfield, M; Guenther, C; Steward, WP; Drevs, J; Lebwohl, D; Wood, J; McSheehy, PMJJournal Article